Stability indicating determination of Albendazole in bulk drug and pharmaceutical dosage form by chromatographic and spectrophotometric methods
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چکیده
منابع مشابه
Stability-indicating HPTLC determination of ambroxol hydrochloride in bulk drug and pharmaceutical dosage form.
A simple, selective, precise, and stability-indicating high-performance thin-layer chromatographic (HPTLC) method for the analysis of ambroxol hydrochloride both as a bulk drug and in formulations was developed and validated. The method employed HPTLC aluminium plates precoated with silica gel 60F-254 as the stationary phase. The solvent system consisted of methanol-triethylamine (4:6 v/v). The...
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BACKGROUND A new, simple, selective, precise, and stability-indicating high-performance thin-layer chromatographic method has been established for analysis of itraconazole (ITZ) in the bulk drug and in pharmaceutical formulations. Separation was achieved on aluminium plate precoated with silica gel 60F254 using Toluene : Chloroform : Methanol [5: 5: 1.5(v/v)] as mobile phase. Densitometric anal...
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Three new methods using titrimetric and spectrophotometry are described for the determination of Propranolol Hydrochloride (PPH) and Atenolol (AN) with potassium bromate as the oxidimetric reagent and acid dyes, Methyl orange and Indigo carmine. In direct titrimetric (method A), the drug is titrated directly with bromate in acid medium and in the presence of excess of bromide using methyl orang...
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A simple, selective, precise and stability indicating high-performance liquid chromatographic method was developed and validated for the determination of pimozide in bulk and pharmaceutical dosage form. The method employed aluminium plates precoated with silica gel 60F-254 as the stationary phase. The solvent system consisted of toluene:acetone:ammonia (5:5:0.1 v/v/v). Compact spot was observed...
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Objective: Four different methods were used for stability indicating determination of aripiprazole in presence of its oxidation product in pure and its dosage form. Methods: The described methods are namely, second derivative spectrophotometry, first-derivative of ratio spectra; bivariate and thin layer chromatography. Results: The derivative spectrophotometric method was based on measuring the...
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ژورنال
عنوان ژورنال: Future Journal of Pharmaceutical Sciences
سال: 2018
ISSN: 2314-7245
DOI: 10.1016/j.fjps.2018.02.001